Ampicillin is a penicillin antibiotic that fights bacteria. Ampicillin is used to treat or prevent many different types of infections such as bladder infections, pneumonia, gonorrhea, meningitis, or infections of the stomach or intestines. Labor and Delivery Oral ampicillin-class antibiotics are poorly absorbed during labor. Studies in guinea pigs showed that intravenous administration of ampicillin slightly decreased the uterine tone and frequency of contractions, Usual Adult Dose for Skin or Soft Tissue Infection. 1.5 to 3 g IV or IM every 6 hours Comments:-The dose is expressed as the total of ampicillin content plus sulbactam content (in a constant 2:1 ratio). This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. DESCRIPTION. UNASYN is an injectable antibacterial combination consisting of the semisynthetic antibacterial ampicillin sodium and the beta-lactamase inhibitor sulbactam sodium for intravenous and intramuscular administration. Vol. 59 / RR-10 Recommendations and Reports 21 foratleast4hoursbeforedelivery;therefore,suchprocedures should be timed accordingly, if possible (CIII). 1.5 g (1 g ampicillin and 0.5 g sulbactam) or 3 g (2 g ampicillin and 1 g sulbactam) IV/IM every 6 hours. For inpatient, non-ICU patients with community-acquired pneumonia (CAP), use in combination with a macrolide antibiotic (azithromycin, clarithromycin, or erythromycin) or with doxycycline. Ampicillin/sulbactam is a combination of the common penicillin-derived antibiotic ampicillin and sulbactam, an inhibitor of bacterial beta-lactamase. 50 mg/kg/dose IV every 6 hours is recommended by the Infectious Diseases Society of America (IDSA) in general; however, higher doses of 75 mg/kg/dose IV every 6 hours are recommended for group B streptococcal (GBS) meningitis. Medscape - Indication-specific dosing for Ampi, Omnipen (ampicillin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.